Which treatment is commonly used for extrapulmonary sarcoidosis such as neurological or cardiac involvement?

• A. Antibiotics
• B. Corticosteroids
• C. Immunoglobulins
• D. Antifungals

Answer: (B)

Extrapulmonary sarcoidosis involves immune-driven granulomatous inflammation in organs like the brain or heart, where controlling the inflammatory process quickly is crucial to prevent lasting damage. Systemic corticosteroids are the most commonly used initial treatment because they effectively and rapidly suppress immune activity, reducing granuloma formation across affected tissues. This makes steroids the preferred option for serious extrapulmonary involvement such as neurosarcoidosis and cardiac sarcoidosis. Antibiotics and antifungals don’t address the underlying inflammatory process of sarcoidosis, and immunoglobulins are not standard first-line therapy for this condition.