Which statement best defines thrombophilia in pregnancy?

• A. A coagulation abnormality with increased risk for thrombosis
• B. A bleeding disorder due to pregnancy
• C. Low platelet count due to heparin
• D. Hypercoagulable state only in postpartum

Answer: (A)

Thrombophilia in pregnancy means a tendency to form clots due to a coagulation system abnormality. Pregnancy itself is a pro-thrombotic state, so having thrombophilia increases the risk of thrombosis during pregnancy and after delivery. The best description is a coagulation abnormality with increased risk for thrombosis. It is not a bleeding disorder, nor is it defined by low platelets from heparin (that describes heparin-induced thrombocytopenia), and the risk is not limited to the postpartum period.