Which of the following is NOT listed as a complication of cystic fibrosis in pregnancy?

• A. Excessive fetal growth (macrosomia)
• B. Preterm birth and labor
• C. Decline in lung function
• D. Glucose intolerance

Answer: (A)

The main idea here is understanding which complications are actually seen with cystic fibrosis during pregnancy. In CF pregnancies, the mother’s lung disease and metabolic status drive most risks. A decline in lung function can occur because pregnancy places extra demands on the respiratory system, and infections or pulmonary exacerbations can worsen respiratory status. Preterm birth and labor are more common as the systemic stress of both conditions can trigger early labor. Glucose intolerance can arise due to pancreatic insufficiency and the potential development of CF-related diabetes, so it’s a recognized obstetric concern in CF.

Excessive fetal growth, or macrosomia, is not typically listed as a complication of cystic fibrosis in pregnancy. CF mothers are often underweight or malnourished, and the fetal growth pattern more commonly risks restriction rather than excess growth. That’s why the description of macrosomia is not considered a standard CF pregnancy complication.