Which of the following is NOT listed as a complication of Cushing's syndrome in pregnancy?

• A. Hypertension
• B. Gestational diabetes mellitus
• C. Heart failure
• D. Hypoglycemia

Answer: (D)

Cushing's syndrome in pregnancy raises cortisol levels that push the body toward higher blood sugar and more fluid retention, which sets the stage for several complications. The excess cortisol promotes gluconeogenesis and causes insulin resistance, so maternal blood glucose tends to rise, increasing the risk of gestational diabetes. It also enhances sodium and water retention and increases vascular sensitivity, which raises blood pressure and can lead to hypertension. The combination of hypertension and fluid overload can put extra strain on the heart, contributing to heart failure. Hypoglycemia, on the other hand, is unlikely in this context because cortisol tends to raise, not lower, blood glucose. So among the options, hypoglycemia is not a listed complication of Cushing's syndrome in pregnancy.