Which inotrope may be used to optimize preload and increase contractility in pulmonary embolus management?

• A. Dobutamine or Dopamine
• B. Epinephrine
• C. Furosemide
• D. Atropine

Answer: (A)

In pulmonary embolism with right‑ventricular strain, the goal is to boost the heart’s ability to pump without markedly increasing the afterload on the already stressed RV. Dobutamine fits this well because it primarily increases beta-1–mediated contractility, which raises stroke volume and cardiac output, and its mild beta-2 effect can cause some vasodilation to lower systemic vascular resistance and reduce RV afterload. Dopamine can also be used at moderate doses to enhance contractility and heart rate, with the potential to support blood pressure if needed. Together, these inotropes help optimize preload and improve forward flow from the RV. In contrast, agents that increase afterload or primarily reduce preload (like diuretics) or that rely on markedly vasoconstrictive effects (like high-dose vasopressors) are less favorable for this specific goal.