Infertility and pregnancy complications are associated with hypopituitarism; which complication is listed as possible during pregnancy?

• A. Anemia
• B. Gestational hypertension
• C. Macrosomia
• D. Prenatal vitamin deficiency

Answer: (B)

Understanding how pituitary dysfunction affects pregnancy helps explain why gestational hypertension can be a possible complication. The pituitary governs several hormones crucial to pregnancy—cortisol via ACTH, thyroid hormone via TSH, and the balance of reproductive hormones via LH/FSH. When pituitary function is reduced, these hormones can be insufficient, altering maternal cardiovascular adaptation and placental development. That disruption can contribute to hypertensive disorders during pregnancy, such as gestational hypertension.

Anemia is common in pregnancy for other reasons (like iron deficiency) and isn’t specifically driven by hypopituitarism. Macrosomia typically relates to maternal diabetes or obesity and excessive fetal glucose exposure, not pituitary hormone deficiency. Prenatal vitamin deficiency is a nutritional issue, not a direct consequence of hypopituitarism. So gestational hypertension is the complication most plausibly linked to hypopituitarism in pregnancy.