Complications of AFLP can mimic preeclampsia, viral hepatitis, and intrahepatic cholestasis, and include liver and kidney failure, infection, hemorrhage, and DIC.

• A. True
• B. False
• C. Only liver failure
• D. Only DIC

Answer: (A)

This statement is true. Acute fatty liver of pregnancy can produce clinical and laboratory findings that resemble preeclampsia, viral hepatitis, and intrahepatic cholestasis, such as jaundice, elevated liver enzymes, malaise, nausea, and coagulation abnormalities. Beyond these overlaps, AFLP can rapidly progress to multiorgan dysfunction, with liver failure and kidney failure being common consequences. The liver’s impaired synthetic function and metabolic disturbances increase the risk of hypoglycemia and coagulopathy, which can lead to hemorrhage and, in severe cases, disseminated intravascular coagulation. The combination of hepatic and systemic effects explains why AFLP can mimic other liver-related disorders while also causing these serious complications. Prompt delivery and supportive care are essential to improve outcomes.